News Downloads About Us Contact Us
Paper Titles
Problems and Options of Integrated Water Resources Management in Nigeria: Administrative Constraints and Policy Strategies
p.12
Biological Degradation of Metribuzin and Profenofos by some Efficient Bacterial Isolates
p.26
Assessment of Biomarker with Special Reference to Antioxidant Level in Blood as Occupational Exposure of Sewage and Garage Workers
p.40
Impact of Intercropping Sorghum and Okra on the Incidence of Flea Beetles of Okra Podagrica spp in Dalwa, Maiduguri Semi-Arid Zone of Nigeria
p.51
Field Evaluation of Two Aqueous Plant Extracts on Water Melon Citrullus lanatus (Thumb) Insect Pets in Northern Guinea Savannah of Nigeria
p.59
Potentiality Assessment of Fish Scale Biodegradation Using Mangrove Fungi Isolated from Indian Sundarban
p.68
Optimization and Production of Alkaline Proteases from Agro Byproducts Using a Novel Trichoderma viridiae Strain VPG 12, Isolated from Agro Soil
p.77
Toxicity Study of Achyranthus aspera
p.85
Effect Methanolic Extract of Achyranthus aspera on Biochemical Status of Albino Mice
p.97

Effect Methanolic Extract of Achyranthus aspera on Biochemical Status of Albino Mice

Article Preview

Abstract:

The effect of administration of Methanolic extract of Achyranthsu asper on biochemical parameter of mice were investigated. This drug induced significant reduction in the cholesterol level and amount of RNA. But significant increase in the amount of glycogen at 25 mg/kg and no significant reduction in the amount of glycogen at 50 mg/kg. This drug also induced increase in the level of alkaline phospatese and decrease in the level of acid phosphatase, protein and DNA, but these changes are statistically not significant. Protein 25 mg shows 4.22 ±0.112 and 50 mg shows 4.05 ±0.085. Cholesterol 25mg shows 0.5 ±0.04 and 50 mg shows 0.39 ±0.038. Glycogen 25mg shows 0.288 ±0.011 and 50mg shows 0.248 ±0.177. DNA 25mg shows 0.109 ±0.039 and 50 mg shows 0.085 ±0.035, RNA 25mg shows 0.38 ±0.036 and 50 mg shows 0.25 ±0.031

By email View Pdf

Info:

Periodical:

International Letters of Natural Sciences (Volume 14)

Pages:

97-105

DOI:

https://doi.org/10.56431/p-6f2a7l

Citation:

Cite this paper

Online since:

April 2014

Authors:

Chinnappa V. Reddy, Abhaykumar Kamble

Keywords:

Achyranthus aspera, Biochemical Parameters, Methanol Extract

Export:

RIS, BibTeX

Permissions:

Creative Commons CC BY 4.0

Share:

Citation:

References

[1] Shankar D., Ved D. K., Indian Forester 129 (2003) 275-287.

Google Scholar

[2] Vijaya Kumar S, Sankar P, Varatharajan R., Pharm Biol 47 (2009) 973-975.

Google Scholar

[3] The Wealth of India; a dictionary of Indian raw materials and industrial products. 1ST ed. III-C. New Delhi: CSIR; 1985, 66-67.

Google Scholar

[4] Dwivedi S., Dubey R., Mehta K., Ethno Leafl. 12 (2008) 670-676.

Google Scholar

[5] Elumalai E. K., Chandrasekaran N., Thirumalai T., Int J Pharmtech Res 1 (2009) 1576-1579.

Google Scholar

[6] Goyal B. R., Goyal R. K., Mehta A. A., A Review: Pharmacognosy Reviews 1 (2007) 143-150.

Google Scholar

[7] Bhosale U. A., Radha Y., Pophale P., Zambare M., Somani R. S., Int J Phytomed. 2 (2010) 440-445.

Google Scholar

[8] Alam M. T., Karim M. M., Khan S. N., J Sci Res 1 (2009) 393-398.

Google Scholar

[9] Vetrichelvan T, Jegadeesan M., Phytother Res. 17 (2003) 77-79.

Google Scholar

[10] Khandelwal K. R., Practical Pharmacognosy. 19th ed. Pune: Nirali Prakashan; 2008, pp.149-56.

Google Scholar

[11] Organization for Economic Cooperation and Development (OECD). OECD guidelines for testing of chemicals test no. 423, acute oral toxicity. France: OECD Publishing; 2006, 1-27.

DOI: 10.1787/9789264071001-en

Google Scholar

[12] Winter C. A., Risley E. A., Nuss G. W., Proc Soc Exp Biol Med 11 (1962) 544-547.

Google Scholar

[13] Perianayagam J. B., Sharma S. K., Pillai K. K., J Ethnopharmacol. 104 (2006) 410-414.

Google Scholar

[14] Sutar N., Garai R., Sharma U., Goyal P., Yadav G., Pharmacie Globale (IJCP) 5 (2011) 1-3.

Google Scholar

[15] S. Palani, S. Raja, D. Venkadesan, S. Karthi, K. Sakthivel, B. Senthil Kumar, Arch. Appl. Sci. Res 1(1) (2009) 18-28. ( Received 22 April 2014; accepted 27 April 2014 )

Google Scholar

© 2025 AOA Academic Open Access Ltd, Cyprus. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For open access content, terms of the Creative Commons licensing CC-BY are applied. AcademicOA.com is a registered trademark of AOA Academic Open Access Ltd, Cyprus.